• Botchwey Lab in Action Converging Technologies
    We combine approaches in medicinal
    chemistry and biomaterials science to
    develop strategies for delivery of naturally
    occuring and biomimetic small molecule
    therapuetics. We also use computational
    network analysis tools to gain important
    insight into local metabolic and cell
    signaling networks that regulate complex
    cell behaviors.
  • Small Molecule Therapies
    Small molecules are particularly appealing
    for regenerative medicine applications
    because many exhibit extended in vivo
    stability, low cost, and scalable
    production. We pursue innovative methods
    for developing small molecules such as
    high throughput functional assays and
    broad-spectrum database analysis techniques
    have to find novel therapetic compounds for
    regenerative medicine.
  • Regenerative Medicine
    The vasculature provides a source of
    nutrients, oxygen, metabolic substrates,
    and access for tissue resident and circulating
    cells that together serve to establish a nice
    for regulating host stem and progenitor cells.
    Our laboratory is investigating how transient
    immuno-regulation using targeted agonists/
    antagonists of S1P receptors can be exploited
    control trafficking of host stem cells, enhance
    tissue vascularization, and resolve

Latest News

January 2, 2015

Quote Of The Week

“Well, it's 1 a.m. Better go home and spend some quality time with the kids." ~ Homer Simpson

January 2, 2015

Welcome to Our Website

It's been a long time coming but the new website is finally here. Connect with us on Facebook or Twitter to let us know how we did.

The Botchwey Laboratory at Georgia Tech and Emory University

The Botchwey Laboratory takes a multidisciplinary approach for improvement of tissue engineering therapies through study of microvascular remodeling, inflammation resolution and host stem cells. Our goal is development of effective new strategies to repair, replace, preserve or enhance tissue or organ function. We are located in the The Parker H. Petit Institute for Bioengineering and Bioscience (IBB) at Georgia Tech.

The Botchwey Lab is supported by:

Measurement of local oxygen concentration within a three-dimensional cell adherent scaffold is valuable in studying and tuning the dynamics of engineered graft success and integration. Find out how ...